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By Dr. Stephen Colucciello
In What's New in Stroke Part 1 we looked at relatively non-controversial topics regarding system issues and supportive care surrounding the ED management of stroke. Now it is time to "bite the bullet" and address the contentious issues surrounding tPA. Since the original National Institute of Neurological Disorders and Stroke (NINDS) study was published in 1995, the lytic controversy has roiled emergency medicine for almost a quarter century.
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